Providing you with a one-stop reference to understand the scientific effects of skincare ingredients

Have you ever turned your favorite skincare products around and checked out the ingredient list? If so, you may have noticed that their names tend to be unfamiliar, long, and ultra-scientific. This can easily baffle consumers and let's be honest? who has the time to learn about each and every ingredient in their skincare routine? 

It can seem daunting to do your research on skincare, which is why most people rely on reviews and guess work. But, did you know that some popular ingredients which have gained traction in the market may even be harming your skin? That's why it's important to debunk the myths and stay educated about what you apply to your skin. After all, the ingredients in both our food and skincare products will ultimately end up in our bodies and play a significant role in our long-term health. Therefore, the same ultra-conscious approach that you take to your diet should also be applied to your skincare.

For example, retinol, arguably the most popular ingredient contained in anti-aging skincare products, has been praised by dermatologists and skincare experts alike for its ability to reduce wrinkles by increasing the production of collagen and stimulating blood flow to the skin (1). However, recent data reveals that retinol can actually deteriorate the skin and increase inflammation, potentially exposing your body to undue harm which could do just the opposite of what you intended in the long term (2,3). We will talk more about that later but the message is: watch out!

On the other hand, some ingredients have rightfully earned their praise for their preventative role in aging and should be strongly considered, especially early in life to get ahead of fine lines and wrinkles. For example, hyaluronic acid can be an incredible tool to maintain healthy skin if used early enough. As one of the most effective hydrators for your skin, integrating oral or topical hyaluronic acid into your normal routine early on in life can keep your young cells functional and prevent collagen breakdown, making your skin less susceptible to the common signs of aging (4,5).

As Dr. Barbara Sturm noted, we have entered a new era of consumer-based skincare, in which consumers are staying educated about ingredients and expect scientific studies to conduct reliable research. OneSkin embraces this new era with open arms and has decided to take the guesswork out of popular ingredients by testing their effects on skin's inflammation, proliferation, senescence, and more. OneSkin is uniquely qualified to educate consumers on this topic, as our scientific team has the ability to test specific ingredients as well any formulation available in the market to evaluate their effect in a cellular and molecular level, distinguishing what is really promoting a beneficial effect from those that are not. 

With this blog series, our goal is to provide you with a one-stop reference for popular ingredients. Our future posts will delve into individual ingredients and provide you with data to break down their true effects. We are excited to start this journey with you? Get ready to become a skincare guru!

1. Retinoid Treatment for Skin Problems: Acne, Wrinkles, & More [Internet]. [cited 2019 Jun 6]. Available from:
2. Park S-H, Lim JS, Jang KL. All-trans retinoic acid induces cellular senescence via upregulation of p16, p21, and p27. Cancer Lett [Internet]. 2011 Nov 28 [cited 2019 Jun 6];310(2):232?9. Available from:
3. Khalil S, Bardawil T, Stephan C, Darwiche N, Abbas O, Kibbi AG, et al. Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects. J Dermatolog Treat [Internet]. 2017 Nov 17 [cited 2019 Jun 6];28(8):684?96. Available from:
4. Oe M, Sakai S, Yoshida H, Okado N, Kaneda H, Masuda Y, et al. Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period. Clin Cosmet Investig Dermatol [Internet]. 2017 [cited 2019 Jun 6];10:267?73. Available from:
5. The Anti-Aging Benefits Of Hyaluronic Acid - HAPPI [Internet]. [cited 2019 Jun 6]. Available from:

OneSkin Team

OneSkin Team

By being able to reprogram the "code of life", we will create new ways of living, and new ways of growing older. OneSkin is developing solutions to enable people to age better, healthier, and with better quality of life. Our mission is to promote people's access to effective anti-aging products, so they can feel and age at their best.

Jun 06, 2019

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